PRODUCTS

Abs / Em : 497 - 517 nm

SPY488-FastAct™ is a fluorescent live cell actin probe specifically designed to capture fast actin dynamics. SPY488-FastAct™ is a bright, green, fluorogenic, non toxic, cell permeable and highly specific live cell probe for fluorescence imaging of actin.

Abs / Em : 512 / 531 nm

SPY505-DNA is a bright green, fluorogenic, non toxic, cell permeable and highly specific live cell DNA probe for fluorescence imaging of the nucleus and DNA.

Abs / Em : 512 / 531 nm

SPY505-CA (also known as MaP510-Halo) is a bright, fluorogenic, cell permeable and green emitting ChloroAlkane substrate for labeling Halo-tag™ in cellular fluorescence imaging experiments.

Abs / Em : 555 / 580 nm

SPY555-DNA is a bright orange, fluorogenic, non toxic, cell permeable and highly specific live cell DNA probe for fluorescence imaging of the nucleus and DNA.

Abs / Em : 555 / 580 nm

SPY555-tubulin is a bright orange, fluorogenic, non toxic, cell permeable and highly specific live cell probe for fluorescence imaging of microtubules.

Abs / Em : 555 / 580 nm

SPY555-actin is a bright, orange, fluorogenic, non toxic, cell permeable and highly specific live cell probe for fluorescence imaging of actin.

Abs / Em : 555 - 580 nm

SPY555-FastAct™ is a fluorescent live cell actin probe specifically designed to capture fast actin dynamics. SPY555-FastAct™ is a bright, orange, fluorogenic, non toxic, cell permeable and highly specific live cell probe for fluorescence imaging of actin.

Abs / Em : 564 - 589 nm

SPY555-FastAct™_X belongs to our most advanced live cell actin imaging probe generation. It labels highly dynamic actin filaments as well as the more static ones. SPY555-FastAct™_X is a bright, fluorogenic, non toxic, cell permeable and highly specific live cell probe for fluorescence imaging of actin. SPY555-FastAct_X can label very fast actin dynamics but lacks undesired F-actin stabilization side effects. It does not require any transfection and works just by adding the probe to the cells and perform imaging a couple of hours later.

Abs / Em : 555 / 580 nm

Peroxi_SPY555 is a bright, orange non toxic, cell permeable and highly specific live cell probe for fluorescence imaging of peroxisomes.

Abs / Em : 555 / 580 nm

SPY555-Golgi is a new fluorescent live cell probe for the golgi apparatus. It is based on asparagusic acid golgi trackers developed by Saidjalolov et al. It is able to label the golgi apparatus in live cells as fast as 15 min after adding the probe. SPY555-Golgi is a bright, non toxic, cell permeable and highly specific live cell probe for fluorescence imaging of the golgi apparatus. It does not require any transfection or genetic manipulation of the cells.

Abs / Em : 566 / 594 nm

BD566-CA is a bright, fluorogenic, cell permeable and orange emitting ChloroAlkane (CA) substrate for Halo-tag™ labeling.

Abs / Em : 555 / 580 nm

SPY555-CA (also known as MaP555-CA or MaP555-Halo) is a bright, fluorogenic, cell permeable and orange emitting ChloroAlkane substrate for labeling Halo-tag™ in cellular fluorescence imaging experiments.

Abs / Em : 599 / 615 nm

SPY595-DNA is a bright, red, fluorogenic, non toxic, cell permeable and highly specific live cell DNA probe for fluorescence imaging of the nucleus and DNA.

Abs / Em : 619 / 636 nm

SPY620-DNA is a bright, red, fluorogenic, non toxic, cell permeable and highly specific live cell DNA probe for fluorescence imaging of the nucleus and DNA.  

Abs / Em : 619 / 636 nm

SPY620-actin is a bright, red, fluorogenic, non toxic, cell permeable and highly specific live cell probe for fluorescence imaging of actin.

Abs / Em : 606 / 626 nm

CPY-CA is a bright, fluorogenic, cell permeable and red emitting ChloroAlkane substrate for labeling Halo-tag™ in cellular fluorescence imaging experiments.

Abs / Em : 626 / 652 nm

BD626-CA is a bright, fluorogenic, cell permeable and red emitting ChloroAlkane (CA) substrate for Halo-tag™ labeling.

Abs / Em : 652 - 674 nm

CenSpark650™ is a first-in-class, cell-permeable small-molecule fluorescent probe engineered specifically for the high-contrast visualization of centrioles, cilia, and flagella without requiring genetic manipulation. Its highly straightforward “add and image” protocol allows for centrioles to be stained as fast as within 1h.

Abs / Em : 652 / 674 nm

SPY650-DNA is a bright, far-red, fluorogenic, non toxic, cell permeable and highly specific live cell DNA probe for fluorescence imaging of the nucleus and DNA.

Abs / Em : 652 / 674 nm

SPY650-tubulin is a bright, far-red, fluorogenic, non toxic, cell permeable and highly specific live cell probe for fluorescence imaging of microtubules.

Abs / Em : 652 - 674 nm

SPY650-FastAct™ is a fluorescent live cell actin probe specifically designed to capture fast actin dynamics. SPY650-FastAct™ is a bright, Far-Red, fluorogenic, non toxic, cell permeable and highly specific live cell probe for fluorescence imaging of actin.

Abs / Em : 652 - 674 nm

SPY650-FastAct_X (Also known as SiR-XActin) is our most advanced live cell actin imaging probe. It labels highly dynamic actin filaments as well as the more static ones. SPY650-FastAct_X is a bright, fluorogenic, non toxic, cell permeable and highly specific live cell probe for fluorescence imaging of actin. SPY650-FastAct_X can label highly dynamic cellular actin structures but lacks undesired F-actin stabilization and toxic side effects. It does not require any transfection and works just by adding the probe to the cells and perform imaging a couple of hours later.

Abs / Em : 652 / 674 nm

Peroxi_SPY650 is a bright, far-red, non toxic, cell permeable and highly specific live cell probe for fluorescence imaging of peroxisomes.

Abs / Em : 652 / 674 nm

SPY650-Golgi is a new fluorescent live cell probe for the golgi apparatus. It is based on asparagusic acid golgi trackers developed by Saidjalolov et al. It is able to label the golgi apparatus in live cells as fast as 15 min after adding the probe. SPY650-Golgi is a bright, non toxic, cell permeable and highly specific live cell probe for fluorescence imaging of the golgi apparatus. It does not require any transfection or genetic manipulation of the cells.

Abs / Em : 652 / 674 nm

SiR-CA (also known as SiR-Halo) is a bright, fluorogenic, cell permeable and far red emitting ChloroAlkane substrate for labeling Halo-tag™ in cellular fluorescence imaging experiments.

Abs / Em : 696 / 718 nm

SPY700-DNA is a far-red, fluorogenic, non toxic, cell permeable and highly specific live cell DNA probe for fluorescence imaging of the nucleus and DNA.

Abs / Em : 696 / 718 nm

SPY700-tubulin is a bright far-red, fluorogenic, cell permeable and highly specific live cell probe for fluorescence imaging of microtubules.

Abs / Em : 696 - 718 nm

SPY700-FastAct™ is a fluorescent live cell actin probe specifically designed to capture fast actin dynamics. SPY700-FastAct™ is a bright, Far-Red, fluorogenic, non toxic, cell permeable and highly specific live cell probe for fluorescence imaging of actin.

Abs / Em : 696 / 718 nm

SPY700-CA (also known as MaP700-Halo) is a bright, fluorogenic, cell permeable and far red emitting ChloroAlkane substrate for labeling Halo-tag™ in cellular fluorescence imaging experiments.

Abs / Em : 652 - 674 nm

Actin_TestKit combines our 3 live cell actin probes SiR-actin, SPY650-FastAct and SPY650-FastAct_X, offering a wide flexibility for actin imaging in live and fixed cells. All the probes are bright, emitting in the far red, fluorogenic, STED compatible and cell permeable. Their complementary properties ensure using the best performing probe under your experimental conditions. Kit contains 3 separate tubes for each actin probe (ca. 20 stainings/tube).

Abs / Em : 512/531 nm | 555/580 nm | 652/674 nm

CA_TestKit combines our 3 Halo-tag™ substrates SPY505-CA, SPY555-CA and SiR-CA, offering a wide flexibility for Halo-tag™ fusion proteins labeling in live and fixed cells. The ligands are all bright, highly fluorogenic, and cell permeable. The 3 fluorophores are covering 3 distinct and very common imaging channels: FITC (green), TMR/Cy3 (orange) and Cy5 (far red). Kit contains 3 separate tubes containing 3 nmol of each Halo-tag™ substrate (ca. 30 stainings/tube**).

Abs / Em : 652 / 674 nm

SiR-DNA is a bright, far-red, fluorogenic, cell permeable and highly specific live cell DNA probe for fluorescence imaging of the nucleus and DNA.

Abs / Em : 652 / 674 nm

SiR-actin is a bright, far red, fluorogenic, non toxic, cell permeable and highly specific live cell probe for fluorescence imaging of actin.

Abs / Em : 652 / 674 nm

SiR-tubulin is a bright, far-red, fluorogenic, non toxic, cell permeable and highly specific live cell probe for fluorescence imaging of microtubules.

Abs / Em : 652 / 674 nm

SiR-lysosome is abright, far red, fluorogenic, cell permeable and highly specific live cell probe for lysosomes.

Abs / Em : 689 / 716 nm

SiR700-DNA is a bright, far-red, fluorogenic, cell permeable and highly specific live cell DNA probe for fluorescence imaging of the nucleus and DNA.

Abs / Em : 689 / 716 nm

SiR700-actin is a bright, far red, fluorogenic, non toxic, cell permeable and highly specific live cell probe for fluorescence imaging of actin.

Abs / Em : 689 / 716nm

SiR700-tubulin is a bright, far-red, fluorogenic, non toxic, cell permeable and highly specific live cell probe for fluorescence imaging of microtubules.

Abs / Em : 689 / 716 nm

SiR700-lysosome is abright, far red, fluorogenic, cell permeable and highly specific live cell probe for lysosomes.

Abs / Em : n.a.

HAK-actin™ is a new tool for Expansion Microscopy that addresses the recurring challenge of reliably staining actin in Expansion Microscopy. HAK-Actin™ is compatible with U-ExM based protocols, including cryo-ExM, and iU-ExM. Its design enables post-expansion labeling, giving you maximum signal, a simplified workflow independent of species specific actin antibodies and freedom to choose your fluorescent label.

Abs / Em : 480 / 600 nm

Flipper-TR^® is a live cell fluorescent plasma membrane tension reporter tailored to the field of mechanobiology.

Abs / Em : 480 / 600 nm

Halo-Flipper is a localizable Flipper-TR^® membrane tension probe using Halo-tag™* as a precise subcellular localization handle. Product contains 1 vial of Halo-Flipper  (10 nmol) in lyophilised form

Abs / Em : 480 / 600 nm

ER Flipper-TR^® is a live cell fluorescent endoplasmic reticulum (ER) membrane tension reporter tailored to the field of mechanobiology.

Abs / Em : 480 / 600 nm

Mito Flipper-TR^® is a live cell fluorescent mitochondrial membrane tension reporter tailored to the field of mechanobiology.

Abs / Em : 480 / 600 nm

Lyso Flipper-TR^® is a live cell fluorescent lysosomal membrane tension reporter tailored to the field of mechanobiology.

Abs / Em : 549 / 569 nm

PKmito RED (also known as PKMR) is a live cell mitochondria imaging probe with very low phototoxicity, high photostability and high brightness. It allows to perform long term imaging of mitochondria

Abs / Em : 591 / 608 nm

PKmito ORANGE (also known as PKMO) is a live cell mitochondria imaging probe with very low phototoxicity, high photostability and high brightness. It allows to perform long term imaging of mitochondria, including STED.

Abs / Em : 591 / 608 nm

PKmito ORANGE FX (also known as PKMO FX) is a unique fluorescent probe for optimized for fixed cell mitochondria imaging. It is highly suited to image mitochonridal cristae structure by STED superresolution microscopy

Abs / Em : 644 / 670 nm

PKmito DEEP RED (also known as PKMDR) is a live cell mitochondria imaging probe with very low phototoxicity, high photostability and high brightness. It allows to perform long term imaging of mitochondria

Abs / Em : 556 / 572 nm

PKmem 555 is a unique fluorescent probe for live or fixed cell plasma membrane imaging. Due to its very low phototoxicity, high photostability and high brightness, it is highly suited for long term imaging of plasma membrane structure and dynamics.

Abs / Em : 590 / 606 nm

PKmem 590 is a unique fluorescent probe for live or fixed cell plasma membrane imaging. Due to its very low phototoxicity, high photostability and high brightness, it is highly suited for long term imaging of plasma membrane structure and dynamics.

Abs / Em : 650 / 671 nm

PKmem 650 is a unique fluorescent probe for live or fixed cell plasma membrane imaging. Due to its very low phototoxicity, high photostability and high brightness, it is highly suited for long term imaging of plasma membrane structure and dynamics.

Abs / Em : 562 / 581 nm

SpyRho 555 is a bright, orange, cell permeable, highly fluorogenic and photostable dye for live cell RNA imaging in combination with the rhodamine binding aptamer RhoBAST.

Abs / Em : 555 / 580 nm

SPY555-BG (also known as MaP555-SNAP) is a bright, fluorogenic, cell permeable and orange emitting benzylguanine substrate for labeling SNAP-tag™ in cellular fluorescence imaging experiments.

Abs / Em : 619 / 636 nm

SPY620-BG (also known as MaP618-SNAP)is a bright, fluorogenic, cell permeable and red emitting benzylguanine substrate for labeling SNAP-tag™ in cellular fluorescence imaging experiments.

Abs / Em : 652 / 674 nm

SiR650-BG (also known as SiR-BG or SiR-SNAP) is a bright, cell permeable and far-red benzylguanine substrate for labeling SNAP-tag™* in cellular fluorescence imaging experiments.

Abs / Em : 696 / 718 nm

SiR700-BG is a bright, cell permeable and far-red benzylguanine substrate for labeling SNAP-tag™* in cellular fluorescence imaging experiments.

Abs / Em : 652 / 674 nm

SiR-COOH ester is the carboxylic acid form of SiR. SiR-COOH can be activated and coupled to ligands or linkers for the preparation of custom conjugates. 1mg and 5 mg pack size available

Abs / Em : 652 / 674 nm

SiR-NHS ester is the active ester form of SiR. SiR-NHS ester reacts with amines to form stable covalent amide bond. 1mg and 5 mg pack size available

Abs / Em : 652 / 674 nm

SiR-maleimide is the 2-maleimidoethyl derivative of SiR. It reacts with thiols and allows the preparation of custom SiR-conjugates. Quantity: 1mg

Abs / Em : 652 / 674 nm

SiR-azide is a clickable derivative of SiR. It reacts with alkynes and allows the preparation of custom SiR-conjugates Quantity: 1mg

Abs / Em : 652 / 674 nm

SiR-alkyne is a clickable derivative of SiR. It reacts with azides and allows the preparation of custom SiR-conjugates. Quantity: 1mg

Abs / Em : 652 / 674 nm

SiR-tetrazine is a clickable derivative of SiR. It reacts with BCN and TCO derivatives. Quantity: 1mg

Abs / Em : 652 / 674 nm

SiR-BCN is a clickable derivative of SiR. It reacts with tetrazine or azide derivatives and allows the preparation of custom SiR-conjugates. Quantity: 1mg