CenSpark650 the first centriole and cilia selective probe.
CenSpark650 the first centriole and cilia selective probe. CenSpark650, a dual-ligand fluorescent probe for centrioles and cilia selective imaging. Visualizing centrioles and cilia in live…
READ MORE
Coming Soon: HAK-actin a new tool for Expansion Microscopy actin imaging
Coming Soon: HAK-actin™, a new tool for Expansion microscopy staining of actin To address the recurring challenge of reliably staining actin in Expansion Microscopy, we will soon offer HAK-Actin, a probe compatible with U-ExM, cryo-ExM,...
READ MORENew Halotag ligands with exceptional brightness and photostability
BD566-CA and BD626-CA Now Available from Spirochrome. Spirochrome is pleased to announce the launch of two additional HaloTag™ ligands—BD566-CA and BD626-CA—built on Zhixing Chen’s outstanding new BriDye™ fluorophores…
SPY650-FastAct_X our newest actin probe
The FastAct™ family expands! We are thrilled to introduce our newest actin probe SPY650-FastAct_X SPY650-FasAct_X features an engineered actin ligand that lacks F-actin stabilization. It is therefore non cytotoxic and thanks to it’s reduced affinity...
READ MORE9 New products available
Announcing Nine New Products: 2 Golgi Probes & 7 HaloTag™ Ligands Products Now Available. We are thrilled to introduce nine new products to our portfolio, including two innovative probes for live-cell imaging of the Golgi...
READ MOREA brand new box for a new Kit
Introducing Our New Packaging Concept and Kit! We are excited to unveil a new packaging concept as part of our 10th-anniversary celebration! Our new box is a true masterpiece, designed with both form and function...
READ MORE10 Years! – New Spirochrome Website
We are very proud to excited to celebrate Spirochrome’s 10th anniversary! It all started back in 2014, the freshly incorporated Spirochrome startup plugged its website online and launched its first 2 probes, SiR-actin and SiR-tubulin...
READ MOREPeroxi_SPY™ probes are available
We proudly introduce the new Peroxi_SPY™ probes for live cell imaging of peroxisomes. Peroxi_SPY™ probes are the first small molecule available on the market to stain specifically peroxisomes. Peroxi_SPY stain peroxisomes in 15 minutes and...
READ MORE3 New PKmem™ probes are available
The three new PKmem™ probe for live or fixed cell plasma membrane imaging are now available. PKmem™ probes were developed by in the lab of Zhixing Chen at Peking university. A BioRxiv preprint ia available...
READ MORENew product PKmito™ ORANGE FX is available
The new PKmito™ ORANGE FX is tailored for fixed cells imaging of mitochondria is now available. PKmito™ ORANGE FX was developed by the team led by Zhixing Chen at Peking university and published in PNAS:...
READ MORENew product coming soon: PKmito ORANGE FX for fixed cell mitochondrial imaging
A new member of the PKmito™ probes family will be available soon! PKmito ORANGE FX is tailored for fixed cells and tissue imaging of mitochondria. The probe was developed by the team led by Zhixing...
READ MOREHaloX™ Exchangeable Halotag Ligands Technology Launch
Spirochrome & Abberior teamed up to bring the HaloX™ exchangeable halotag™ ligands technology1) available to the imaging community. Unlike regular Chloroalkane ligands, that react covalently with Halotag™ protein, HaloX™ ligands bind reversibly to Halotag™ protein....
READ MOREWe launch SPyRho 555, a new fluorogenic dye for live cell RNA imaging.
SpyRho 555 is a fluorogenic dye ligand for the RNA aptamer RhoBAST developed by the lab of Murat Sunbul in Heidelberg University1). SpyRho 555 is a rhodamine dye that is cell permeable, highly fluorogenic and photostable....
READ MOREPKmito™ probes for live cell mitochondria imaging are available.
To launch PKmito™ probes in style, we are offering a 50% discount until March 31st 2023! PKmito™ probes are bright and photostable fluorescent probes for gentle imaging of mitochondria in live cells. They have been...
READ MORESPY700-FastAct™ is available
After introducing SPY650-FastAct™ and SPY555-FastAct™, we are proud to announce that SPY700-FastAct™ is available, expanding our FastAct™ product line further into the far-red. Our FastAct™ technology is a unique fluorescent live cell actin imaging tool....
READ MOREPKmito™ probes for live cell mitochondria imaging will be available in January 2023 through our distributors network.
PKmito™ probes are bright and photostable fluorescent probes for gentle imaging of mitochondria in live cells. They have been developed and published by the lab Zhixing Chen from Peking University1,2) PKmito™ probes feature a unique...
READ MORESPY555-FastAct™ is available
After introducing SPY650-FastAct™ last year, we are proud to announce that SPY555-FastAct™ is available, expanding our FastAct™ product line into the TMR/Cy3 channel. Our FastAct™ technology is a new and unique fluorescent live cell actin...
READ MORESPY555-FastAct™ soon available
Following the footsteps of our new actin probe SPY650-FastAct™, we proudly announce that SPY555-FastAct™ will soon be available. Our FastAct™ technology is a new and unique fluorescent live cell actin imaging tool. It labels very...
READ MORESPY650-FastAct™ is available.
Spirochrome’s new actin probe, SPY650-FastAct™ is available. SPY650-FastAct™ is a new and unique fluorescent live cell actin probe. It labels very dynamic actin filaments as well as the more static ones. SPY650-FastAct™ is a bright,...
READ MORENew probe coming soon
We proudly announce that we will soon launch a new product line: FastAct™ The first product, SPY650-FastAct™ is able to label very dynamic actin, it is cell permeable, bright, photostable and fluorogenic. It’s far red...
READ MORENew distributor in Switzerland
Spirochrome is pleased to announce it has appointed Lubio Science as its exclusive distributor for all Spirochrome products in Switzerland. We are looking forward to this new collaboration with Lubio Science.
GIVEAWAY PROMOTION!
The Spiro Swiss army knife kits are here. If you’re a US customer, please visit our US distributor webpage to know how to get yours! For Our EU customers, visit our EU distributor webpage to...
READ MOREThe Spiro Swiss army knives are coming soon!
Keep an eye on our social media, Spirochrome website or distributor websites for more info how to get these!
The new organelle specific mechanosensitive Flipper-TR™ probes are available!
We introduce new Flipper-TR™ probes that target ER, mitochondria & lysosomes of live cells. Those were developped by NCCR Chemical Biology groups of Aurelien Roux and Stefan Matile in a recent article1) ER Flipper-TR Mito...
READ MOREOur new SPY620 probes are here!
We are proud to introduce our new red emitting SPY™ probes based on Map618 fluorophore developed by the Johnsson group in Heidelberg.1) SPY620-actin is a highly fluorogenic probe for F-actin with a turn-on ratio above...
READ MOREComing soon: SPY620 probes
Spirochrome will soon introduce new red emitting SPY™ probes based on the Map618 fluorophore developed in the Johnsson group in Heidelberg.1) SPY620-actin for F-actin and SPY620-DNA for nucleus staining as well as SPY620-BG for SNAP-tag...
READ MOREThe Flipper-TR family expands!
Spirochrome will soon introduce new Flipper-TR™ probes that target ER, mitochondria & lysosomes within live cells. Those were previously introduced by NCCR Chemical Biology groups of Aurelien Roux and Stefan Matile in a recent article1)...
READ MORESpirochrome now provides highly cell permeable benzylguanine (BG) derivatives of SiR and SPY™ dyes . BG derivatives are substrates to the self-labeling tag SNAP-tag™*.
Our new BG derivatives of SiR and SPY™ fluorophores are live cell compatible substrates for SNAP-tag™* bearing fluorophores with high brightness, high photostability which are compatible with superresolution microscopy (STED & SIM) 1-3). SPY555-BG, SiR650-BG...
READ MORE
