The new organelle specific mechanosensitive Flipper-TR™ probes are available!
2 October 2020
We introduce new Flipper-TR™ probes that target ER, mitochondria & lysosomes of live cells. Those were developped by NCCR Chemical Biology groups of Aurelien Roux and Stefan Matile in a recent article1)
1. “Mechanosensitive Fluorescent Probes to Image Membrane Tension in Mitochondria, Endoplasmic Reticulum, and Lysosomes”; Antoine Goujon, et. al.;J. Am. Chem. Soc. 141, 8, 3380–3384, 2019.
live Cos7 cells labeled with ER Flipper-TR™. Courtesy of N. Schilling, D. Haenni & U. Ziegler; Center for Microscopy and Image Analysis; University of Zurich Switzerland.
FLIM image of live Cos7 cells labeled with Mito Flipper-TR™. Courtesy of N. Schilling, D. Haenni & U. Ziegler; Center for Microscopy and Image Analysis; University of Zurich Switzerland.
