We proudly introduce the new Peroxi_SPY™ probes for live cell imaging of peroxisomes. Peroxi_SPY™ probes are the first small molecule available on the market to stain specifically peroxisomes. Peroxi_SPY stain peroxisomes in 15 minutes and do not require any genetic modification or transfection/transduction. Peroxi_SPY™ probes have been developed by the team led by Triana Amen […]
The three new PKmem™ probe for live or fixed cell plasma membrane imaging are now available. PKmem™ probes were developed by in the lab of Zhixing Chen at Peking university. A BioRxiv preprint ia available online: A gentle palette of plasma membrane dyes PKmem probes™ are now available from Spirochrome through our usual distributors with […]
The new PKmito™ ORANGE FX is tailored for fixed cells imaging of mitochondria is now available. PKmito™ ORANGE FX was developed by the team led by Zhixing Chen at Peking university and published in PNAS: An aldehyde-crosslinking mitochondrial probe for STED imaging in fixed cells PKmito ORANGE FX is now available at Spirochrome through our […]
A new member of the PKmito™ probes family will be available soon! PKmito ORANGE FX is tailored for fixed cells and tissue imaging of mitochondria. The probe was developed by the team led by Zhixing Chen at Peking university and published in PNAS: An aldehyde-crosslinking mitochondrial probe for STED imaging in fixed cells The outstanding STED […]
Spirochrome & Abberior teamed up to bring the HaloX™ exchangeable halotag™ ligands technology1) available to the imaging community. Unlike regular Chloroalkane ligands, that react covalently with Halotag™ protein, HaloX™ ligands bind reversibly to Halotag™ protein. This unique feature allows, in addition to regular confocal microscopy, to perform STED, PAINT or MINFLUX superresolution imaging. During […]
SpyRho 555 is a fluorogenic dye ligand for the RNA aptamer RhoBAST developed by the lab of Murat Sunbul in Heidelberg University1). SpyRho 555 is a rhodamine dye that is cell permeable, highly fluorogenic and photostable. With its high affinity and fast on/off binding kinetics to its cognate aptamer RhoBAST, it allows overcoming the main issues […]
To launch PKmito™ probes in style, we are offering a 50% discount until March 31st 2023! PKmito™ probes are bright and photostable fluorescent probes for gentle imaging of mitochondria in live cells. They have been developed by the lab Zhixing Chen from Peking University1,2) Your browser does not support the video tag. Live HeLa cells […]
After introducing SPY650-FastAct™ and SPY555-FastAct™, we are proud to announce that SPY700-FastAct™ is available, expanding our FastAct™ product line further into the far-red. Our FastAct™ technology is a unique fluorescent live cell actin imaging tool. SPY700-FastAct™ labels very dynamic actin filaments as well as the more static ones. In conjugation with our SPY700 fluorophore it […]
PKmito™ probes are bright and photostable fluorescent probes for gentle imaging of mitochondria in live cells. They have been developed and published by the lab Zhixing Chen from Peking University1,2) PKmito™ probes feature a unique technology: They consist of cyanine derivatives bearing intramolecular cyclooctatetraene (COT) substituents. The presence of intramolecular COT substituents very efficiently reduces […]
After introducing SPY650-FastAct™ last year, we are proud to announce that SPY555-FastAct™ is available, expanding our FastAct™ product line into the TMR/Cy3 channel. Our FastAct™ technology is a new and unique fluorescent live cell actin imaging tool. SPY555-FastAct™ labels very dynamic actin filaments as well as the more static ones. In conjugation with our bright […]
